KEGG   Homo sapiens (human): 79258
Entry
79258             CDS       T01001                                 
Symbol
MMEL1, MMEL2, NEP2, NEPII, NL1, NL2, SEP
Name
(RefSeq) membrane metalloendopeptidase like 1
  KO
K08635  neprilysin [EC:3.4.24.11]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    79258 (MMEL1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     79258 (MMEL1)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M13: neprilysin family
   79258 (MMEL1)
SSDB
Motif
Pfam: Peptidase_M13_N Peptidase_M13 ERAP1_C
Other DBs
NCBI-GeneID: 79258
NCBI-ProteinID: NP_258428
OMIM: 618104
HGNC: 14668
Ensembl: ENSG00000142606
UniProt: Q495T6 B3KS82
Position
1:complement(2590639..2633016)
AA seq 779 aa
MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS
RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC
GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV
IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND
DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL
VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS
SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV
NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV
ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS
LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ
ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW
DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA
QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW
NT seq 2340 nt   +upstreamnt  +downstreamnt
atggggaagtccgaaggcccagtggggatggtggagagcgccggccgtgcagggcagaag
cgcccggggttcctggagggggggctgctgctgctgctgctgctggtgaccgctgccctg
gtggccttgggtgtcctctacgccgaccgcagagggaagcagctgccacgccttgctagc
cggctgtgcttcttacaggaggagaggacctttgtaaaacgaaaaccccgagggatccca
gaggcccaagaggtgagcgaggtctgcaccacccctggctgcgtgatagcagctgccagg
atcctccagaacatggacccgaccacggaaccgtgtgacgacttctaccagtttgcatgc
ggaggctggctgcggcgccacgtgatccctgagaccaactcaagatacagcatctttgac
gtcctccgcgacgagctggaggtcatcctcaaagcggtgctggagaattcgactgccaag
gaccggccggctgtggagaaggccaggacgctgtaccgctcctgcatgaaccagagtgtg
atagagaagcgaggctctcagcccctgctggacatcttggaggtggtgggaggctggccg
gtggcgatggacaggtggaacgagaccgtaggactcgagtgggagctggagcggcagctg
gcgctgatgaactcacagttcaacaggcgcgtcctcatcgacctcttcatctggaacgac
gaccagaactccagccggcacatcatctacatagaccagcccaccttgggcatgccctcc
cgagagtactacttcaacggcggcagcaaccggaaggtgcgggaagcctacctgcagttc
atggtgtcagtggccacgttgctgcgggaggatgcaaacctgcccagggacagctgcctg
gtgcaggaggacatggtgcaggtgctggagctggagacacagctggccaaggccacggta
ccccaggaggagagacacgacgtcatcgccttgtaccaccggatgggactggaggagctg
caaagccagtttggcctgaagggatttaactggactctgttcatacaaactgtgctatcc
tctgtcaaaatcaagctgctgccagatgaggaagtggtggtctatggcatcccctacctg
cagaaccttgaaaacatcatcgacacctactcagccaggaccatacagaactacctggtc
tggcgcctggtgctggaccgcattggtagcctaagccagagattcaaggacacacgagtg
aactaccgcaaggcgctgtttggcacaatggtggaggaggtgcgctggcgtgaatgtgtg
ggctacgtcaacagcaacatggagaacgccgtgggctccctctacgtcagggaggcgttc
cctggagacagcaagagcatggtcagagaactcattgacaaggtgcggacagtgtttgtg
gagacgctggacgagctgggctggatggacgaggagtccaagaagaaggcgcaggagaag
gccatgagcatccgggagcagatcgggcaccctgactacatcctggaggagatgaacagg
cgcctggacgaggagtactccaatctgaacttctcagaggacctgtactttgagaacagt
ctgcagaacctcaaggtgggcgcccagcggagcctcaggaagcttcgggaaaaggtggac
ccaaatctctggatcatcggggcggcggtggtcaatgcgttctactccccaaaccgaaac
cagattgtattccctgccgggatcctccagccccccttcttcagcaaggagcagccacag
gccttgaactttggaggcattgggatggtgatcgggcacgagatcacgcacggctttgac
gacaatggccggaacttcgacaagaatggcaacatgatggattggtggagtaacttctcc
acccagcacttccgggagcagtcagagtgcatgatctaccagtacggcaactactcctgg
gacctggcagacgaacagaacgtgaacggattcaacacccttggggaaaacattgctgac
aacggaggggtgcggcaagcctataaggcctacctcaagtggatggcagagggtggcaag
gaccagcagctgcccggcctggatctcacccatgagcagctcttcttcatcaactatgcc
caggtgtggtgcgggtcctaccggcccgagttcgccatccaatccatcaagacagacgtc
cacagtcccctgaagtacagggtactggggtcgctgcagaacctggccgccttcgcagac
acgttccactgtgcccggggcacccccatgcaccccaaggagcgatgccgcgtgtggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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